ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Immunoglobulin kappa chain variable 12-41

Intramolecular
Cysteine 134 and cysteine 43
A redox-regulated disulphide may form within Immunoglobulin kappa chain variable 12-41 between cysteines 134 and 43 (134 and 194 respectively in this structure).

Details

Redox score ?
nan
PDB code
1qbl
Structure name
fab e8 (fabe8a) x-ray structure at 2
Structure deposition date
1998-04-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01635
Residue number A
134
Residue number B
43
Peptide name
Immunoglobulin kappa chain variable 12-41

Ligandability

Cysteine 134 of Immunoglobulin kappa chain variable 12-41

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 43 of Immunoglobulin kappa chain variable 12-41

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 134 in protein A could not be asigned to a Uniprot residue.
Uncertain whether structure cysteine 194 has been assigned to correct residue.
If this tool was useful for finding a disulphide, please cite: